BDBM8738 1-[(4-methylphenyl)methyl]-4-(thiophen-2-yl)-1H-imidazole::Disubstituted imidazole 1

SMILES Cc1ccc(Cn2cnc(c2)-c2cccs2)cc1

InChI Key InChIKey=UMOFOLLUKPBVQG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8738   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
Glaxosmithkline

LigandPNGBDBM8738(1-[(4-methylphenyl)methyl]-4-(thiophen-2-yl)-1H-im...)
Affinity DataIC50:  1.37E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Glaxosmithkline

LigandPNGBDBM8738(1-[(4-methylphenyl)methyl]-4-(thiophen-2-yl)-1H-im...)
Affinity DataIC50:  1.24E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed